The Required Coefficient of Friction for evaluating gait alterations in people with Multiple Sclerosis during gait

Pacifici, Ilaria;Galli, Manuela;Kleiner, Ana;CORONA, FEDERICA;COGHE, GIANCARLO;MARONGIU, ELISABETTA;Loi, Andrea;CRISAFULLI, ANTONIO;COCCO, ELEONORA;MARROSU, MARIA GIOVANNA;PAU, MASSIMILIANO

2016-01-01

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Abstract

Background Required Coefficient of Friction (RCOF) is one of the most critical gait parameters associated to the occurrence of slipping in individuals affected by neurological disorders characterized by balance impairments. This study aims to calculate RCOF in people with Multiple Sclerosis (MS) on the basis of three-dimensional Gait Analysis (GA) data. Methods This study enrolls twenty-two people with MS (pwMS) who were charaterized by an Expanded Disability Status Score in the range 1.5 to 6 and 10 healthy controls (HC). All participants underwent to three-dimensional GA from which we extracted kinematic and kinetic data (i.e. the Ground Reaction Forces, GRF, and joint moments and powers in the sagittal plane). RCOF was calculated as the ratio of the shear to normal GRF components during the stance phase of gait cycle, and normalized by the walking velocity. Thus, the following variables were extracted: first peak (named P1COF), valley (named V1COF), and second peak (named P2COF) in RCOF curve; also computingting the maximum ankle dorsi-plantarflexion moment (MOMmax) and the maximum ankle joint power (PWRmax). Results Our data revealed that P2COF results are significantly lower in pwMS when compared to HC (p= 0.043; Z = -2.025). In pwMS, the study found a moderate, positive correlation between V1COF and MOMmax (r=0.558; p< 0.001 and a moderate, positive correlation between EDSS score and MOMmax (ρ=0.622.;p= 0.001). While in HC group, the study detected a moderate positive correlation between P1COF and MOM max (r = 0.636; p = 0.008). Conclusion Friction during mid stance and push off phases is critically important to determine whether the frictional capabilities of foot/floor interface are sufficient to prevent slips in subjects with MS. The impaired ankle momentin MS group causes increased P2COF in comparison to HC, increasing the risk of slipping in the critical phase of transmission of the developed forces to kinematic chain. Also, the correlation analysis among RCOF values and kinetic variables describe the interplay between V1COF and MOMmax: the higher V1COF is, the higher is MOMmax; and the different correlation the study found between COF and kinetic paramters in MS and HC group highlighted the different gait patterns of the two classes of subjects.