Synthesis of some novel 2,6-disubstituted pyridazin-3-ones as TMC120 analogues
LODDO, ROBERTA
2007-01-01
Abstract
Different analogues of TMC120 derived from pyridazin-3(2H)-one rings were synthesized by coupling of 3,6-dichloropyridazine with arylacetonitriles, phenols and/or aniline derivative followed by hydrolysis and alkylation with different benzyl bromide derivatives.Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.