A novel synthetic route for the anti-HIV drug MC-1220 and its analogues

LODDO, ROBERTA;
2010-01-01

Abstract

Herein we describe a novel and practical synthesis of the anti-HIV compound MC-1220. Through the use of inexpensive reagents and commercially available starting materials, MC-1220 and its analogues are more easily accessed by a four-step procedure involving a key reduction step.
2010
Inglese
5
11
1847
1849
3
http://dx.doi.org/10.1002/cmdc.201000244
Esperti anonimi
internazionale
scientifica
Antiviral agents; Grignard reaction; HIV; MC-1220; NNRTIs; Pyrimidines
Loksha, Ym; Globisch, D; Loddo, Roberta; Collu, G; LA COLLA, P; Pedersen, Eb
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
6
reserved
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