Thyroid dysfunction in patients with metastatic carcinoma treated with Sunitinib: is thyroid autoimmunity involved?

PANI, FABIANA;BOI, FRANCESCO;MARIOTTI, STEFANO
2015-01-01

Abstract

Sunitinib is a tyrosine kinase inhibitor (TKI) inducing thyroid dysfunction, but the precise mechanism(s) involved remains to be explained, including a role of thyroid autoimmunity. The objective was to evaluate thyroid function, parameters of autoimmunity, and thyroid ultrasound findings in patients with metastatic cancer and normal thyroid function/autoimmunity before the initiation of Sunitinib therapy. This is a prospective, observational cohort study.
2015
Inglese
THYROID
25
11
1255
1261
7
WOS:000364331800012
2-s2.0-84946811554
26414109
Esperti anonimi
internazionale
scientifica
no
Pani, Fabiana; Atzori, F; Baghino, G; Boi, Francesco; Tanca, L; Ionta, Mt; Mariotti, Stefano
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
7
partially_open
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