Synthesis of some new (2(1H)-pyridones from 3-amino-3-(dialkylamino)propenenitriles

Cocco MT;CONGIU, CENZO;Maccioni A;ONNIS, VALENTINA

1992-01-01

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Abstract

3-Amino-3-(dialkylamino)propenenitriles were reacted with acetylenecarboxylates to give 2(1H)-pyridone derivatives. The reaction with ethyl propynate afforded dienamino ester intermediates which cyclized in sodium ethoxide/ethanol to 5-cyano-2(1H)-pyridone. The reaction with diethyl acetylenedicarboxylate gave directly the 2(1H)-pyridone derivatives.