University of Cagliari
reserved
A metabolomic study of preterm human and formula milk by high resolution NMR and GC/MS analysis: preliminary results
CESARE MARINCOLA, FLAMINIA;NOTO, ANTONIO;CABONI, PIERLUIGI;BARBERINI, LUIGI;ATZORI, LUIGI;FANOS, VASSILIOS
2012-01-01
Abstract
OBJECTIVE: The aim of the present study was to investigate the metabolic profile of preterm human breast milk (HBM) by using a metabolomic approach. METHODS: NMR spectroscopy and GC/MS were used to analyze the water-soluble and lipid fractions extracted from milk samples obtained from mothers giving birth at 26-36 weeks of gestation. For the sake of comparison, preterm formula milk was also studied. RESULTS: The multivariate statistical analysis of the data evidenced biochemical variability both between preterm HBM and commercial milk and within the group of HBM samples. CONCLUSIONS: The preliminary results of this study suggest that metabolomics may provide a promising tool to study aspects related to the nutrition and health of preterm infant.
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| JMFNM Milk.pdf Solo gestori archivio
Type: versione editoriale
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Format Adobe PDF
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