University of Cagliari
none
Synthesis of new fluorinated 1,5-benzoxazepine derivatives
CONGIU, CENZO;ONNIS, VALENTINA;
1997-01-01
Abstract
A simple approach to the fluorinated 1,5-benzoxazepine ring system is described. By reacting commercially accessible aminophenols 1 and the trifluoroacetylvinyl ether 2, high yields of enaminones 3 were obtained. Functionalization of methyl group of compounds 3 gave rise to dieneamines 4 that were cyclized in acidic environment to benzoxazepine derivatives 5.
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