Enzo Tramontano
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Enzo Tramontano

Showing results 1 to 50 of 240
Title Issue Date Author(s) Journal Publisher
New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors 1-Jan-2024 Messore, Antonella; Malune, Paolo; Patacchini, Elisa; Noemi Madia, Valentina; Ialongo, Davide; Arpacioglu, Merve; Albano, Aurora; Ruggieri, Giuseppe; Saccoliti, Francesco; Scipione, Luigi; Tramontano, Enzo; Canton, Serena; Corona, Angela; Scognamiglio, Sante; Paulis, Annalaura; Suleiman, Mustapha; Mohammed Al-Maqtari, Helmi; Abid, Fatma Mohamed A.; Kawsar, Sarkar M. A.; Sankaranarayanan, Murugesan; Di Santo, Roberto; Esposito, Francesca; Roberta Costi, And PHARMACEUTICALS -
Identification of new benzofuran derivatives as STING agonists with broad-spectrum antiviral activity 1-Jan-2024 Paulis, A.; Onali, A.; Vidalain, P. O.; Lotteau, V.; Jaquemin, C.; Corona, A.; Distinto, S.; Delogu, G. L.; Tramontano, E. VIRUS RESEARCH -
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex 1-Jan-2024 Kuzikov, Maria; Reinshagen, Jeanette; Wycisk, Krzysztof; Corona, Angela; Esposito, Francesca; Malune, Paolo; Manelfi, Candida; Iaconis, Daniela; Beccari, Andrea; Tramontano, Enzo; Nowotny, Marcin; Windshügel, Bjorn; Gribbon, Philip; Zaliani, Andrea VIRUS RESEARCH -
The Stability of Social and Behavioral Rhythms and Unexpected Low Rate of Relevant Depressive Symptoms in Old Adults during the COVID-19 Pandemic 1-Jan-2024 Sancassiani, Federica; Cossu, Giulia; Cantone, Elisa; Romano, Ferdinando; Perra, Alessandra; Urban, Antonio; Pinna, Samantha; Del Giacco, Stefano; Littera, Roberto; Firinu, Davide; Chessa, Luchino; Tramontano, Enzo; Nardi, Antonio Egidio; Carta, Mauro Giovanni JOURNAL OF CLINICAL MEDICINE -
Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication 1-Jan-2023 Asthana, A.; Corona, A.; Shin, W. -J.; Kwak, M. -J.; Gaughan, C.; Tramontano, E.; Jung, J. U.; Schobert, R.; Jha, B. K.; Silverman, R. H.; Biersack, B. VIRUSES -
Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting the main protease Mpro 1-Jan-2023 Biolatti, Matteo; Blangetti, Marco; Baggieri, Melissa; Marchi, Antonella; Gioacchini, Silvia; Bajetto, Greta; Arnodo, Davide; Bucci, Paola; Fioravanti, Raoul; Kojouri, Maedeh; Bersani, Matteo; D’Arrigo, Giulia; Siragusa, Lydia; Ghinato, Simone; De Andre, Marco; Gugliesi, Francesca; Albano, Camilla; Pasquero, Selina; Visentin, Ivan; D’Ugo, Emilio; Esposito, Francesca; Malune, Paolo; Tramontano, Enzo; Prandi, Cristina; Spyrakis, Francesca; Magurano, Fabio; Dell’Oste, Valentina ACS INFECTIOUS DISEASES -
Versatile anti-infective properties of pyrido- and dihydropyrido[2,3-d]pyrimidine-based compounds 1-Jan-2023 Al Nasr, Ibrahim S; Corona, Angela; Koko, Waleed S; Khan, Tariq A; Ben Said, Ridha; Daoud, Ismail; Rahali, Seyfeddine; Tramontano, Enzo; Schobert, Rainer; Amdouni, Noureddine; Biersack, Bernhard BIOORGANIC & MEDICINAL CHEMISTRY -
Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication 1-Jan-2023 Corona, Angela; Madia, Valentina Noemi; De Santis, Riccardo; Manelfi, Candida; Emmolo, Roberta; Ialongo, Davide; Patacchini, Elisa; Messore, Antonella; Amatore, Donatella; Faggioni, Giovanni; Artico, Marco; Iaconis, Daniela; Talarico, Carmine; Di Santo, Roberto; Lista, Florigio; Costi, Roberta; Tramontano, Enzo ANTIVIRAL RESEARCH -
Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome 1-Jan-2023 Scognamiglio, Sante; Grandi, Nicole; Pessiu, Eleonora; Tramontano, Enzo VIRUS RESEARCH -
5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action 1-Jan-2023 Corona, A.; Meleddu, R.; Delelis, O.; Subra, F.; Cottiglia, F.; Esposito, F.; Distinto, S.; Maccioni, E.; Tramontano, E. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY -
Human Endogenous Retrovirus (HERV) Transcriptome Is Dynamically Modulated during SARS-CoV-2 Infection and Allows Discrimination of COVID-19 Clinical Stages 1-Jan-2023 Grandi, Nicole; Erbì, Maria Chiara; Scognamiglio, Sante; Tramontano, Enzo MICROBIOLOGY SPECTRUM -
Unlocking STING as a Therapeutic Antiviral Strategy 1-Jan-2023 Paulis, A.; Tramontano, E. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES -
HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France) 1-Jan-2023 Sanna, Cinzia; D’Abrosca, Brigida; Fiorentino, Antonio; Giammarino, Federica; Vicenti, Ilaria; Corona, Angela; Caredda, Alessia; Tramontano, Enzo; Esposito, Francesca PHARMACEUTICALS -
Visible Light-Mediated Inactivation of H1N1 Virus UsingPolymer-Based Heterojunction Photocatalyst 1-Jan-2023 Porcu, Stefania; Maloccu, Stefania; Corona, Angela; Hazra, Moulika; David, TULLIA CARLA; Chiriu, Daniele; Carbonaro, CARLO MARIA; Tramontano, Enzo; Ricci, PIER CARLO POLYMERS -
Naïve antibody library derived monoclonal antibody against VP35 of Ebola virus 1-Jan-2023 Lai, Jing Yi; Corona, Angela; Ng, Chong Lee; Tramontano, Enzo; Choong, Yee Siew; Lim, Theam Soon INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES -
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses 1-Jan-2023 Fumagalli, Valeria; Di Lucia, Pietro; Ravà, Micol; Marotta, Davide; Bono, Elisa; Grassi, Stefano; Donnici, Lorena; Cannalire, Rolando; Stefanelli, Irina; Ferraro, Anastasia; Esposito, Francesca; Pariani, Elena; Inverso, Donato; Montesano, Camilla; Delbue, Serena; Perlman, Stanley; Tramontano, Enzo; De Francesco, Raffaele; Summa, Vincenzo; Guidotti, Luca G; Iannacone, Matteo EMBO MOLECULAR MEDICINE -
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination 1-Jan-2023 Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY -
Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity 1-Jan-2023 Tocco, G.; Canton, S.; Laus, A.; Caboni, P.; Le Grice, S. F. J.; Tramontano, E.; Esposito, F. MOLECULES -
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach 1-Jan-2023 Alessandra Ambrosio, Francesca; Costa, Giosuè; Romeo, Isabella; Esposito, Francesca; Alkhatib, Mohammad; Salpini, Romina; Svicher, Valentina; Corona, Angela; Malune, Paolo; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Alcaro, Stefano; Anna Artese, And JOURNAL OF CHEMICAL INFORMATION AND MODELING -
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action 1-Jan-2023 Iaconis, Daniela; Caccuri, Francesca; Manelfi, Candida; Talarico, Carmine; Bugatti, Antonella; Filippini, Federica; Zani, Alberto; Novelli, Rubina; Kuzikov, Maria; Ellinger, Bernhard; Gribbon, Philip; Riecken, Kristoffer; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Beccari, Andrea Rosario; Caruso, Arnaldo; Allegretti, Marcello VIRUSES -
Comparing the responses of countries and National Health Systems to the COVID-19 pandemic: a critical analysis with a case-report series 1-Jan-2023 Carta, M. G.; Orru, G.; Littera, R.; Firinu, D.; Chessa, L.; Cossu, G.; Primavera, D.; DEL GIACCO, S.; Tramontano, E.; Manocchio, N.; Buonomo, C.; Scano, A. EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES -
Ebola virus disease: In vivo protection provided by the PAMP restricted TLR3 agonist rintatolimod and its mechanism of action 1-Jan-2023 Corona, Angela; Strayer, David; Distinto, Simona; Daino, Gian Luca; Paulis, Annalaura; Tramontano, Enzo; Mitchell, William M ANTIVIRAL RESEARCH -
Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function 1-Jan-2023 Boniardi, Irene; Corona, Angela; Basquin, Jerome; Basquin, Claire; Milia, Jessica; Nagy, István; Tramontano, Enzo; Zinzula, Luca VIRUS RESEARCH -
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort 1-Jan-2022 Zaliani, Andrea; Vangeel, Laura; Reinshagen, Jeanette; Iaconis, Daniela; Kuzikov, Maria; Keminer, Oliver; Wolf, Markus; Ellinger, Bernhard; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Manelfi, Candida; Herzog, Katja; Jochmans, Dirk; De Jonghe, Steven; Chiu, Winston; Francken, Thibault; Schepers, Joost; Collard, Caroline; Abbasi, Kayvan; Claussen, Carsten; Summa, Vincenzo; Beccari, Andrea R.; Neyts, Johan; Gribbon, Philip; Leyssen, Pieter SCIENTIFIC DATA -
Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration 1-Jan-2022 Richetta, Clémence; Subra, Frédéric; Malet, Isabelle; Leh, Hervé; Charpentier, Charlotte; Corona, Angela; Collin, Gilles; Descamps, Diane; Deprez, Eric; Parissi, Vincent; Calvez, Vincent; Tramontano, Enzo; Marcelin, Anne-Geneviève; Delelis, Olivier JOURNAL OF VIROLOGY -
Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach 1-Jan-2022 Romeo, Isabella; Ambrosio, Francesca Alessandra; Costa, Giosuè; Corona, Angela; Alkhatib, Mohammad; Salpini, Romina; Lemme, Saverio; Vergni, Davide; Svicher, Valentina; Santoro, Maria Mercedes; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Artese, Anna; Alcaro, Stefano MOLECULES -
Genomic Snapshot of SARS-CoV-2 in Migrants Entering Through Mediterranean Sea Routes 1-Jan-2022 Grandi, N.; Paglietti, B.; Cusano, R.; Ibba, G.; Lai, V.; Piu, C.; Angioj, F.; Serra, C.; Kelvin, D. J.; Tramontano, E.; Rubino, S. FRONTIERS IN PUBLIC HEALTH -
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production 1-Jan-2022 Corona, Angela; Fanunza, Elisa; Salata, Cristiano; Morwitzer, Melody Jane; Distinto, Simona; Zinzula, Luca; Sanna, Cinzia; Frau, Aldo; Daino, Gian Luca; Quartu, Marina; Taglialatela-Scafati, Orazio; Rigano, Daniela; Reid, Stpatrick; Mirazimi, Alì; Tramontano, Enzo ANTIVIRAL RESEARCH -
Prolonged activity of HERV-K(HML2) in Old World Monkeys accounts for recent integrations and novel recombinant variants 1-Jan-2022 Chabukswar, S.; Grandi, N.; Tramontano, E. FRONTIERS IN MICROBIOLOGY -
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route 1-Jan-2022 Pelliccia, Sveva; Cerchia, Carmen; Esposito, Francesca; Cannalire, Rolando; Corona, Angela; Costanzi, Elisa; Kuzikov, Maria; Gribbon, Philip; Zaliani, Andrea; Brindisi, Margherita; Storici, Paola; Tramontano, Enzo; Summa, Vincenzo EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY -
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities 1-Jan-2022 Corona, Angela; Wycisk, Krzysztof; Talarico, Carmine; Manelfi, Candida; Milia, Jessica; Cannalire, Rolando; Esposito, Francesca; Gribbon, Philip; Zaliani, Andrea; Iaconis, Daniela; Beccari, Andrea R.; Summa, Vincenzo; Nowotny, Marcin; Tramontano, Enzo ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE -
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity 1-Jan-2022 Nizi, Maria Giulia; Persoons, Leentje; Corona, Angela; Felicetti, Tommaso; Cernicchi, Giada; Massari, Serena; Manfroni, Giuseppe; Vangeel, Laura; Barreca, Maria Letizia; Esposito, Francesca; Jochmans, Dirk; Milia, Jessica; Cecchetti, Violetta; Schols, Dominique; Neyts, Johan; Tramontano, Enzo; Sabatini, Stefano; De Jonghe, Steven; Tabarrini, Oriana ACS MEDICINAL CHEMISTRY LETTERS -
Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase–associated RNase H function 1-Jan-2021 Fois, Benedetta; Corona, Angela; Tramontano, Enzo; Distinto, Simona; Maccioni, Elias; Meleddu, Rita; Caboni, Pierluigi; Floris, Costantino; Cottiglia, Filippo JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY -
Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from Scrophularia trifoliata 1-Jan-2021 Guzzo, Francesca; Russo, Rosita; Sanna, Cinzia; Celaj, Odeta; Caredda, Alessia; Corona, Angela; Tramontano, Enzo; Fiorentino, Antonio; Esposito, Francesca; D’Abrosca, Brigida MOLECULES -
HERV‐K(HML7) integrations in the human genome: Comprehensive characterization and comparative analysis in non‐human primates 1-Jan-2021 Grandi, N.; Pisano, M. P.; Pessiu, E.; Scognamiglio, S.; Tramontano, E. BIOLOGY -
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds 1-Jan-2021 Sanna, C.; Marengo, A.; Acquadro, S.; Caredda, A.; Lai, R.; Corona, A.; Tramontano, E.; Rubiolo, P.; Esposito, F. PLANTS -
The Methanolic Extract of Perilla frutescens Robustly Restricts Ebola Virus Glycoprotein-Mediated Entry 1-Jan-2021 Kuo, Yu-Ting; Liu, Ching-Hsuan; Corona, Angela; Fanunza, Elisa; Tramontano, Enzo; Lin, Liang-Tzung VIRUSES -
Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2 1-Jan-2021 Fanunza, Elisa; Carletti, Fabrizio; Quartu, Marina; Grandi, Nicole; Ermellino, Laura; Milia, Jessica; Corona, Angela; Capobianchi, Maria Rosaria; Ippolito, Giuseppe; Tramontano, Enzo VIRULENCE -
Structural and biochemical analysis of the dual inhibition of mg-132 against sars-cov-2 main protease (Mpro/3clpro) and human cathepsin-l 1-Jan-2021 Costanzi, E.; Kuzikov, M.; Esposito, F.; Albani, S.; Demitri, N.; Giabbai, B.; Camasta, M.; Tramontano, E.; Rossetti, G.; Zaliani, A.; Storici, P. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES -
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen 1-Jan-2021 Kuzikov, Maria; Costanzi, Elisa; Reinshagen, Jeanette; Esposito, Francesca; Vangeel, Laura; Wolf, Markus; Ellinger, Bernhard; Claussen, Carsten; Geisslinger, Gerd; Corona, Angela; Iaconis, Daniela; Talarico, Carmine; Manelfi, Candida; Cannalire, Rolando; Rossetti, Giulia; Gossen, Jonas; Albani, Simone; Musiani, Francesco; Herzog, Katja; Ye, Yang; Giabbai, Barbara; Demitri, Nicola; Jochmans, Dirk; De Jonghe, Steven; Rymenants, Jasper; Summa, Vincenzo; Tramontano, Enzo; Beccari, Andrea R.; Leyssen, Pieter; Storici, Paola; Neyts, Johan; Gribbon, Philip; Zaliani, Andrea ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE -
Integration of SARS-CoV-2 RNA in infected human cells by retrotransposons: an unlikely hypothesis and old viral relationships 1-Jan-2021 Grandi, N.; Tramontano, E.; Berkhout, B. RETROVIROLOGY -
Garcinol from Garcinia indica inhibits HIV-1 reverse transcriptase-associated ribonuclease H 1-Jan-2021 Corona, Angela; Seibt, Sebastian; Schaller, David; Schobert, Rainer; Volkamer, Andrea; Biersack, Bernhard; Tramontano, Enzo ARCHIV DER PHARMAZIE -
Inhibitors of Ebolavirus targeting innate immune evasion 1-Jan-2021 Paulis, A. L.; Corona, A.; Tramontano, E. ANNUAL REPORTS IN MEDICINAL CHEMISTRY -
Human endogenous retroviruses (HERVs) and mammalian apparent Ltrs retrotransposons (MALRs) are dynamically modulated in different stages of immunity 1-Jan-2021 Pisano, M. P.; Grandi, N.; Tramontano, E. BIOLOGY -
Enhanced antitumoral activity of TLR7 agonists via activation of human endogenous retroviruses by HDAC inhibitors 1-Jan-2021 Diaz-Carballo, D.; Saka, S.; Acikelli, A. H.; Homp, E.; Erwes, J.; Demmig, R.; Klein, J.; Schroer, K.; Malak, S.; D'Souza, F.; Noa-Bolano, A.; Menze, S.; Pano, E.; Andrioff, S.; Teipel, M.; Dammann, P.; Klein, D.; Nasreen, A.; Tannapfel, A.; Grandi, N.; Tramontano, E.; Ochsenfarth, C.; Strumberg, D. COMMUNICATIONS BIOLOGY -
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase 1-Jan-2021 Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Ialongo, Davide; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto JOURNAL OF MEDICINAL CHEMISTRY -
Retrotransposons as drivers of Mammalian brain evolution 1-Jan-2021 Ferrari, R.; Grandi, N.; Tramontano, E.; Dieci, G. LIFE -
INMI1 Zika Virus NS4B Antagonizes the Interferon Signaling by Suppressing STAT1 Phosphorylation 1-Jan-2021 Fanunza, Elisa; Grandi, Nicole; Quartu, Marina; Carletti, Fabrizio; Ermellino, Laura; Milia, Jessica; Corona, Angela; Rosaria Capobianchi, Maria; Ippolito, Giuseppe; Tramontano, Enzo VIRUSES -
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions 1-Jan-2021 Meleddu, Rita; Corona, Angela; Distinto, Simona; Cottiglia, Filippo; Deplano, Serenella; Sequeira, Lisa; Secci, Daniela; Onali, Alessia; Sanna, Erica; Esposito, Francesca; Cirone, Italo; Ortuso, Francesco; Alcaro, Stefano; Tramontano, Enzo; Mátyus, Péter; Maccioni, Elias MOLECULES -
Natural and Nature-Derived Products Targeting Human Coronaviruses 1-Jan-2021 Vougogiannopoulou, Konstantina; Corona, Angela; Tramontano, Enzo; Alexis, Michael N.; Skaltsounis, Alexios-Leandros MOLECULES -
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