University of Cagliari
Gianfranco Balboni
Investigation on Hydrazonobenzenesulfonamides as Human Carbonic Anhydrase I, II, IX and XII Inhibitors
2023-01-01 Moi, Davide; Vittorio, Serena; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Bv8 mediates myeloid cell migration and enhances malignancy of colorectal cancer
2023-01-01 Li, Xiaomeng; Chang, Enqiang; Cui, Jiang; Zhao, Hailin; Hu, Cong; O'Dea, Kieran P; Tirlapur, Nikhil; Balboni, Gianfranco; Zhang, Jiaqiang; Ying, Liming; Ma, Daqing
Prokineticin System Is a Pharmacological Target to Counteract Pain and Its Comorbid Mood Alterations in an Osteoarthritis Murine Model
2023-01-01 Galimberti, Giulia; Amodeo, Giada; Magni, Giulia; Riboldi, Benedetta; Balboni, Gianfranco; Onnis, Valentina; Ceruti, Stefania; Sacerdote, Paola; Franchi, Silvia
Prokineticin 1 is a novel factor regulating porcine corpus luteum function
2023-01-01 Baryla, Monika; Goryszewska-Szczurek, Ewelina; Kaczynski, Piotr; Balboni, Gianfranco; Waclawik, Agnieszka
Synthesis of Sulfonamides Incorporating Piperidinyl-Hydrazidoureido and Piperidinyl-Hydrazidothioureido Moieties and Their Carbonic Anhydrase I, II, IX and XII Inhibitory Activity
2023-01-01 Moi, Davide; Deplano, Alessandro; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
The Impact of UFP-512 in Mice with Osteoarthritis Pain: The Role of Hydrogen Sulfide
2023-01-01 Batallé, Gerard; Bai, Xue; Balboni, Gianfranco; Pol, Olga
Blocking prokineticin receptors attenuates synovitis and joint destruction in collagen-induced arthritis
2023-01-01 Impellizzeri, Daniela; Maftei, Daniela; Severini, Cinzia; Miele, Rossella; Balboni, Gianfranco; Siracusa, Rosalba; Cordaro, Marika; Di Paola, Rosanna; Cuzzocrea, Salvatore; Lattanzi, Roberta
Hydrogen Sulfide Increases the Analgesic Effects of µ- and δ-Opioid Receptors during Neuropathic Pain: Pathways Implicated
2022-01-01 Bai, Xue; Batallé, Gerard; Balboni, Gianfranco; Pol, Olga
A Critical Role of δ-Opioid Receptor in Anti-microglial Activation Under Stress
2022-01-01 Xu, Yuan; Zhi, Feng; Peng, Ya; Mao, Jiahao; Balboni, Gianfranco; Yang, Yilin; Xia, Ying
Hydrogen sulfide inhibits inflammatory pain and enhances the analgesic properties of delta opioid receptors
2021-01-01 Porta, A.; Rodriguez, L.; Bai, X.; Batalle, G.; Roch, G.; Pouso-Vazquez, E.; Balboni, G.; Pol, O.
The antagonism of the prokineticin system counteracts bortezomib induced side effects: Focus on mood alterations
2021-01-01 Amodeo, G.; Verduci, B.; Sartori, P.; Procacci, P.; Conte, V.; Balboni, G.; Sacerdote, P.; Franchi, S.
Differential inflammation-mediated function of prokineticin 2 in the synovial fibroblasts of patients with rheumatoid arthritis compared with osteoarthritis
2021-01-01 Noda, K.; Dufner, B.; Ito, H.; Yoshida, K.; Balboni, G.; Straub, R. H.
Evidence-Based View of Safety and Effectiveness of Prokineticin Receptors Antagonists during Pregnancy
2021-01-01 Reynaud, Deborah; Sergent, Frederic; Abi Nahed, Roland; Traboulsi, Wael; Collet, Constance; Marquette, Christel; Hoffmann, Pascale; Balboni, Gianfranco; Zhou, Qun-Yong; Murthi, Padma; Benharouga, Mohamed; Alfaidy, Nadia
Hair Growth Promotion by δ-Opioid Receptor Activation
2021-01-01 Zheng, Mei; Choi, Nahyun; Balboni, Gianfranco; Xia, Ying; Sung, Jong-Hyuk
Prokineticin 1-prokineticin receptor 1 signaling promotes angiogenesis in the porcine endometrium during pregnancy
2020-01-01 Goryszewska, E.; Kaczynski, P.; Balboni, G.; Waclawik, A.
Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors
2020-01-01 Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Piras, Valentina; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
∂-opioid receptor activation protects against Parkinson’s disease-related mitochondrial dysfunction by enhancing PINK1/Parkin-dependent mitophagy
2020-01-01 Xu, Y.; Zhi, F.; Mao, J.; Peng, Y.; Shao, N.; Balboni, G.; Yang, Y.; Xia, Y.
Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors
2020-01-01 Nocentini, Alessio; Moi, Davide; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles
2020-01-01 Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina
In-Vitro Evaluation of Antioxidant, Antiproliferative and Photo-Protective Activities of Benzimidazolehydrazone Derivatives
2020-01-01 Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina
Opposite Roles of δ- and μ-Opioid Receptors in BACE1 Regulation and Alzheimer’s Injury
2020-01-01 Xu, Y.; Zhi, F.; Balboni, G.; Yang, Y.; Xia, Y.
Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation
2019-01-01 Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones
2019-01-01 Demurtas, Monica; Baldisserotto, Anna; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina
Antagonistic Activity of Naphthoquinone-Based Hybrids toward Amyloids Associated with Alzheimer's Disease and Type-2 Diabetes
2019-01-01 Tyrrell, PAUL ANTHONY; Viswanathan, G. K.; Mahapatra, S.; Balboni, G.; Pacifico, S.; Gazit, E.; Segal, D.
Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy
2019-01-01 Moschetti, Giorgia; Amodeo, Giada; Maftei, Daniela; Lattanzi, Roberta; Procacci, Patrizia; Sartori, Patrizia; Balboni, Gianfranco; Onnis, Valentina; Conte, Vincenzo; Panerai, Alberto; Sacerdote, Paola; Franchi, Silvia
Prokineticin 2 promotes and sustains neuroinflammation in vincristine treated mice: Focus on pain and emotional like behavior
2019-01-01 Moschetti, G.; Amodeo, G.; Paladini, M. S.; Molteni, R.; Balboni, G.; Panerai, A.; Sacerdote, P.; Franchi, S.
δ-Opioid Receptor Activation Attenuates Hypoxia/MPP+-Induced Downregulation of PINK1: a Novel Mechanism of Neuroprotection Against Parkinsonian Injury
2019-01-01 Xu, Yuan; Zhi, Feng; Peng, Ya; Shao, Naiyuan; Khiati, Dhiaedin; Balboni, Gianfranco; Yang, Yilin; Xia, Ying
Treatment With the Delta Opioid Agonist UFP-512 Alleviates Chronic Inflammatory and Neuropathic Pain: Mechanisms Implicated
2019-01-01 Polo, Sara; Díaz, Andrés Felipe; Gallardo, Núria; Leánez, Sergi; Balboni, Gianfranco; Pol, Olga
Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors
2019-01-01 Moi, Davide; Foster, Paul A.; Rimmer, Lucy G.; Jaffri, Alisha; Deplano, Alessandro; Balboni, Gianfranco; Onnis, Valentina; Potter, Barry V. L.
The prokineticin receptor antagonist PC1 rescues memory impairment induced by β amyloid administration through the modulation of prokineticin system
2019-01-01 Maftei, Daniela; Ratano, Patrizia; Fusco, Ilaria; Marconi, Veronica; Squillace, Silvia; Negri, Lucia; Severini, Cinzia; Balboni, Gianfranco; Steardo, Luca; Bronzuoli, Maria Rosanna; Scuderi, Caterina; Campolongo, Patrizia; Lattanzi, Roberta
Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors
2018-01-01 Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Onnis, Valentina; Supuran, Claudiu T.
Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity
2018-01-01 Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina
Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy
2018-01-01 Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Salvadori, Severo; Onnis, Valentina; Supuran, Claudiu T.
Prokineticin system modulation as a new target to counteract the amyloid beta toxicity induced by glutamatergic alterations in an in vitro model of Alzheimer's disease
2017-01-01 Caioli, Silvia; Severini, Cinzia; Ciotti, Teresa; Florenzano, Fulvio; Pimpinella, Domenico; Petrocchi Passeri, Pamela; Balboni, Gianfranco; Polisca, Patrizio; Lattanzi, Roberta; Nisticò, Robert; Negri, Lucia; Zona, Cristina
Antagonism of EG-VEGF receptors as targeted therapy for choriocarcinoma progression in vitro and in vivo
2017-01-01 Traboulsi, Wael; Sergent, Frederic; Boufettal, Houssine; Brouillet, Sophie; Slim, Rima; Hoffmann, Pascale; Benlahfid, Mohammed; Zhou, qun yong; Balboni, Gianfranco; Onnis, Valentina; Bolze, Pierre Adrien; Salomon, Aude; Sauthier, Philippe; Mallet, François; Aboussaouira, Touria; Feige, Jean Jacques; Benharouga, Mohamed; Alfaidy, Nadia
3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes
2017-01-01 Park, Byeongyeon; Nam, Ji Hye; Kim, Jin Han; Kim, Hyoung Ja; Onnis, Valentina; Balboni, Gianfranco; Lee, Kyung Tae; Park, Jeong Ho; Catto, Marco; Carotti, Angelo; Lee, Jae Yeol
Antagonism of EG-VEGF receptors is a novel targeted therapy for choriocarcinoma progression: in vitro, in vivo and in clinical studies
2017-01-01 Traboulsi, Wael; Sergent, Fréderic; Brouillet, Sophie; Boufettal, Houssine; Hoffmann, Pascale; Zhou, Qun yong; Balboni, Gianfranco; Aboussaouira, Touria; Feige, Jean jacques; Benharouga, Mohamed; Alfaidy, Nadia
Genetically Encodable Bacterial Flavin Transferase for Fluorogenic Protein Modification in Mammalian Cells
2017-01-01 Kang, Myeong Gyun; Park, Jumi; Balboni, Gianfranco; Lim, Mi Hee; Lee, Changwook; Rhee, Hyun Woo
DESIGN, SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF NEW DNA METHYLTRANSFERASE INHIBITORS
2016-01-01 Balboni, Gianfranco; Deplano, Alessandro; Demurtas, Monica; Arimondo, Paola B.; Masson, Veronique; Onnis, Valentina
DIHYDROQUINAZOLINE BENZYLAMIDES AS ACETYLCHOLINESTERASE AND BUTYRYLCHOLINESTERASE INHIBITORS
2016-01-01 Onnis, Valentina; Balboni, Gianfranco; Deplano, Alessandro; Demurtas, Monica; Buyn, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Catto, Marco; Pisani, Leonardo; Carotti, Angelo
Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones
2016-01-01 Onnis, Valentina; Demurtas, Monica; Deplano, Alessandro; Balboni, Gianfranco; Baldisserotto, A; Manfredini, S; Pacifico, S; Liekens, S; Balzarini, J.
Effect of the T-type channel blocker KYS-05090S in mouse models of acute and neuropathic pain
2016-01-01 M'Dahoma, Saïd; Gadotti, Vinicius M; Zhang, Fang Xiong; Park, Byeongyeon; Nam, Ji Hye; Onnis, Valentina; Balboni, Gianfranco; Lee, Jae Yeol; Zamponi, Gerald W.
Attenuating Ischemic Disruption of K+ Homeostasis in the Cortex of Hypoxic-Ischemic Neonatal Rats: DOR Activation vs. Acupuncture Treatment
2016-01-01 Chao, Dongman; Wang, Qinyu; Balboni, Gianfranco; Ding, Guanghong; Xia, Ying
Prokineticins are neuroprotective in models of cerebral ischemia and ischemic tolerance in vitro
2016-01-01 Landucci, E; Lattanzi, R; Gerace, E; Scartabelli, T; Balboni, Gianfranco; Negri, L; Pellegrini Giampietro, De
Synthesis and SIRT1 modulation studies of amides and hydrazides of benzoic acid incorporating a (2-trifluoromethylpyridin-4-yl)amino moiety
2015-01-01 Congiu, Cenzo; Balboni, Gianfranco; Onnis, Valentina
TRPV1 modulators: synthesis and in vitro evaluation of 1-heteroarylpiperidinecarboxamide and piperazinylurea derivatives
2015-01-01 Congiu, Cenzo; Onnis, Valentina; Balboni, Gianfranco; Schiano Moriello, A; Di Marzo, V; De Petrocellis, L.
Dihydroquinazoline and Triazinedione Derivatives as Prok1 and Prok2 receptor antagonists in HEK-293 transfected cells
2015-01-01 Balboni, Gianfranco; Congiu, Cenzo; Deplano, Alessandro; Demurtas, Monica; Buyn, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Sbai, Oualid; Rondard, Philippe; Onnis, Valentina
Prokineticin 2 upregulation in the peripheral nervous system has a major role in triggering and maintaining neuropathic pain in the chronic constriction injury model
2015-01-01 Lattanzi, R; Maftei, D; Marconi, V; Florenzano, F; Franchi, S; Borsani, E; Rodella, Lf; Balboni, Gianfranco; Salvadori, S; Sacerdote, P; Negri, L.
Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity
2015-01-01 Severini, C.; Lattanzi, R.; Maftei, D.; Marconi, V.; Ciotti, M. T.; Petrocchi Passeri, P.; Florenzano, F.; Del Duca, E.; Caioli, S.; Zona, C.; Balboni, Gianfranco; Salvadori, S.; Nistico, R.; Negri, L.
Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives
2015-01-01 Sakakibara, Norikazu; Balboni, Gianfranco; Congiu, Cenzo; Onnis, Valentina; Demizu, Yosuke; Misawa, Takashi; Kurihara, Masaaki; Kato, Yoshihisa; Maruyama, Tokumi; Toyama, Masaaki; Okamoto, Mika; Baba, Masanori
| Title | Issue Date | Author(s) | Journal | Publisher |
|---|---|---|---|---|
| Investigation on Hydrazonobenzenesulfonamides as Human Carbonic Anhydrase I, II, IX and XII Inhibitors | 1-Jan-2023 | Moi, Davide; Vittorio, Serena; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | MOLECULES | - |
| Bv8 mediates myeloid cell migration and enhances malignancy of colorectal cancer | 1-Jan-2023 | Li, Xiaomeng; Chang, Enqiang; Cui, Jiang; Zhao, Hailin; Hu, Cong; O'Dea, Kieran P; Tirlapur, Nikhil; Balboni, Gianfranco; Zhang, Jiaqiang; Ying, Liming; Ma, Daqing | FRONTIERS IN IMMUNOLOGY | - |
| Prokineticin System Is a Pharmacological Target to Counteract Pain and Its Comorbid Mood Alterations in an Osteoarthritis Murine Model | 1-Jan-2023 | Galimberti, Giulia; Amodeo, Giada; Magni, Giulia; Riboldi, Benedetta; Balboni, Gianfranco; Onnis, Valentina; Ceruti, Stefania; Sacerdote, Paola; Franchi, Silvia | CELLS | - |
| Prokineticin 1 is a novel factor regulating porcine corpus luteum function | 1-Jan-2023 | Baryla, Monika; Goryszewska-Szczurek, Ewelina; Kaczynski, Piotr; Balboni, Gianfranco; Waclawik, Agnieszka | SCIENTIFIC REPORTS | - |
| Synthesis of Sulfonamides Incorporating Piperidinyl-Hydrazidoureido and Piperidinyl-Hydrazidothioureido Moieties and Their Carbonic Anhydrase I, II, IX and XII Inhibitory Activity | 1-Jan-2023 | Moi, Davide; Deplano, Alessandro; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | MOLECULES | - |
| The Impact of UFP-512 in Mice with Osteoarthritis Pain: The Role of Hydrogen Sulfide | 1-Jan-2023 | Batallé, Gerard; Bai, Xue; Balboni, Gianfranco; Pol, Olga | ANTIOXIDANTS | - |
| Blocking prokineticin receptors attenuates synovitis and joint destruction in collagen-induced arthritis | 1-Jan-2023 | Impellizzeri, Daniela; Maftei, Daniela; Severini, Cinzia; Miele, Rossella; Balboni, Gianfranco; Siracusa, Rosalba; Cordaro, Marika; Di Paola, Rosanna; Cuzzocrea, Salvatore; Lattanzi, Roberta | JOURNAL OF MOLECULAR MEDICINE | - |
| Hydrogen Sulfide Increases the Analgesic Effects of µ- and δ-Opioid Receptors during Neuropathic Pain: Pathways Implicated | 1-Jan-2022 | Bai, Xue; Batallé, Gerard; Balboni, Gianfranco; Pol, Olga | ANTIOXIDANTS | - |
| A Critical Role of δ-Opioid Receptor in Anti-microglial Activation Under Stress | 1-Jan-2022 | Xu, Yuan; Zhi, Feng; Peng, Ya; Mao, Jiahao; Balboni, Gianfranco; Yang, Yilin; Xia, Ying | FRONTIERS IN AGING NEUROSCIENCE | - |
| Hydrogen sulfide inhibits inflammatory pain and enhances the analgesic properties of delta opioid receptors | 1-Jan-2021 | Porta, A.; Rodriguez, L.; Bai, X.; Batalle, G.; Roch, G.; Pouso-Vazquez, E.; Balboni, G.; Pol, O. | ANTIOXIDANTS | - |
| The antagonism of the prokineticin system counteracts bortezomib induced side effects: Focus on mood alterations | 1-Jan-2021 | Amodeo, G.; Verduci, B.; Sartori, P.; Procacci, P.; Conte, V.; Balboni, G.; Sacerdote, P.; Franchi, S. | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Differential inflammation-mediated function of prokineticin 2 in the synovial fibroblasts of patients with rheumatoid arthritis compared with osteoarthritis | 1-Jan-2021 | Noda, K.; Dufner, B.; Ito, H.; Yoshida, K.; Balboni, G.; Straub, R. H. | SCIENTIFIC REPORTS | - |
| Evidence-Based View of Safety and Effectiveness of Prokineticin Receptors Antagonists during Pregnancy | 1-Jan-2021 | Reynaud, Deborah; Sergent, Frederic; Abi Nahed, Roland; Traboulsi, Wael; Collet, Constance; Marquette, Christel; Hoffmann, Pascale; Balboni, Gianfranco; Zhou, Qun-Yong; Murthi, Padma; Benharouga, Mohamed; Alfaidy, Nadia | BIOMEDICINES | - |
| Hair Growth Promotion by δ-Opioid Receptor Activation | 1-Jan-2021 | Zheng, Mei; Choi, Nahyun; Balboni, Gianfranco; Xia, Ying; Sung, Jong-Hyuk | BIOMOLECULES & THERAPEUTICS | - |
| Prokineticin 1-prokineticin receptor 1 signaling promotes angiogenesis in the porcine endometrium during pregnancy | 1-Jan-2020 | Goryszewska, E.; Kaczynski, P.; Balboni, G.; Waclawik, A. | BIOLOGY OF REPRODUCTION | - |
| Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors | 1-Jan-2020 | Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Piras, Valentina; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | BIOORGANIC CHEMISTRY | - |
| ∂-opioid receptor activation protects against Parkinson’s disease-related mitochondrial dysfunction by enhancing PINK1/Parkin-dependent mitophagy | 1-Jan-2020 | Xu, Y.; Zhi, F.; Mao, J.; Peng, Y.; Shao, N.; Balboni, G.; Yang, Y.; Xia, Y. | AGING | - |
| Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors | 1-Jan-2020 | Nocentini, Alessio; Moi, Davide; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles | 1-Jan-2020 | Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina | BIOORGANIC CHEMISTRY | - |
| In-Vitro Evaluation of Antioxidant, Antiproliferative and Photo-Protective Activities of Benzimidazolehydrazone Derivatives | 1-Jan-2020 | Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina | PHARMACEUTICALS | - |
| Opposite Roles of δ- and μ-Opioid Receptors in BACE1 Regulation and Alzheimer’s Injury | 1-Jan-2020 | Xu, Y.; Zhi, F.; Balboni, G.; Yang, Y.; Xia, Y. | FRONTIERS IN CELLULAR NEUROSCIENCE | - |
| Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation | 1-Jan-2019 | Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones | 1-Jan-2019 | Demurtas, Monica; Baldisserotto, Anna; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina | BIOORGANIC CHEMISTRY | - |
| Antagonistic Activity of Naphthoquinone-Based Hybrids toward Amyloids Associated with Alzheimer's Disease and Type-2 Diabetes | 1-Jan-2019 | Tyrrell, PAUL ANTHONY; Viswanathan, G. K.; Mahapatra, S.; Balboni, G.; Pacifico, S.; Gazit, E.; Segal, D. | ACS CHEMICAL NEUROSCIENCE | - |
| Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy | 1-Jan-2019 | Moschetti, Giorgia; Amodeo, Giada; Maftei, Daniela; Lattanzi, Roberta; Procacci, Patrizia; Sartori, Patrizia; Balboni, Gianfranco; Onnis, Valentina; Conte, Vincenzo; Panerai, Alberto; Sacerdote, Paola; Franchi, Silvia | JOURNAL OF NEUROINFLAMMATION | - |
| Prokineticin 2 promotes and sustains neuroinflammation in vincristine treated mice: Focus on pain and emotional like behavior | 1-Jan-2019 | Moschetti, G.; Amodeo, G.; Paladini, M. S.; Molteni, R.; Balboni, G.; Panerai, A.; Sacerdote, P.; Franchi, S. | BRAIN BEHAVIOR AND IMMUNITY | - |
| δ-Opioid Receptor Activation Attenuates Hypoxia/MPP+-Induced Downregulation of PINK1: a Novel Mechanism of Neuroprotection Against Parkinsonian Injury | 1-Jan-2019 | Xu, Yuan; Zhi, Feng; Peng, Ya; Shao, Naiyuan; Khiati, Dhiaedin; Balboni, Gianfranco; Yang, Yilin; Xia, Ying | MOLECULAR NEUROBIOLOGY | - |
| Treatment With the Delta Opioid Agonist UFP-512 Alleviates Chronic Inflammatory and Neuropathic Pain: Mechanisms Implicated | 1-Jan-2019 | Polo, Sara; Díaz, Andrés Felipe; Gallardo, Núria; Leánez, Sergi; Balboni, Gianfranco; Pol, Olga | FRONTIERS IN PHARMACOLOGY | - |
| Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors | 1-Jan-2019 | Moi, Davide; Foster, Paul A.; Rimmer, Lucy G.; Jaffri, Alisha; Deplano, Alessandro; Balboni, Gianfranco; Onnis, Valentina; Potter, Barry V. L. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| The prokineticin receptor antagonist PC1 rescues memory impairment induced by β amyloid administration through the modulation of prokineticin system | 1-Jan-2019 | Maftei, Daniela; Ratano, Patrizia; Fusco, Ilaria; Marconi, Veronica; Squillace, Silvia; Negri, Lucia; Severini, Cinzia; Balboni, Gianfranco; Steardo, Luca; Bronzuoli, Maria Rosanna; Scuderi, Caterina; Campolongo, Patrizia; Lattanzi, Roberta | NEUROPHARMACOLOGY | - |
| Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors | 1-Jan-2018 | Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Onnis, Valentina; Supuran, Claudiu T. | BIOORGANIC CHEMISTRY | - |
| Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity | 1-Jan-2018 | Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy | 1-Jan-2018 | Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Salvadori, Severo; Onnis, Valentina; Supuran, Claudiu T. | BIOORGANIC CHEMISTRY | - |
| Prokineticin system modulation as a new target to counteract the amyloid beta toxicity induced by glutamatergic alterations in an in vitro model of Alzheimer's disease | 1-Jan-2017 | Caioli, Silvia; Severini, Cinzia; Ciotti, Teresa; Florenzano, Fulvio; Pimpinella, Domenico; Petrocchi Passeri, Pamela; Balboni, Gianfranco; Polisca, Patrizio; Lattanzi, Roberta; Nisticò, Robert; Negri, Lucia; Zona, Cristina | NEUROPHARMACOLOGY | - |
| Antagonism of EG-VEGF receptors as targeted therapy for choriocarcinoma progression in vitro and in vivo | 1-Jan-2017 | Traboulsi, Wael; Sergent, Frederic; Boufettal, Houssine; Brouillet, Sophie; Slim, Rima; Hoffmann, Pascale; Benlahfid, Mohammed; Zhou, qun yong; Balboni, Gianfranco; Onnis, Valentina; Bolze, Pierre Adrien; Salomon, Aude; Sauthier, Philippe; Mallet, François; Aboussaouira, Touria; Feige, Jean Jacques; Benharouga, Mohamed; Alfaidy, Nadia | CLINICAL CANCER RESEARCH | - |
| 3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes | 1-Jan-2017 | Park, Byeongyeon; Nam, Ji Hye; Kim, Jin Han; Kim, Hyoung Ja; Onnis, Valentina; Balboni, Gianfranco; Lee, Kyung Tae; Park, Jeong Ho; Catto, Marco; Carotti, Angelo; Lee, Jae Yeol | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | Elsevier Ltd |
| Antagonism of EG-VEGF receptors is a novel targeted therapy for choriocarcinoma progression: in vitro, in vivo and in clinical studies | 1-Jan-2017 | Traboulsi, Wael; Sergent, Fréderic; Brouillet, Sophie; Boufettal, Houssine; Hoffmann, Pascale; Zhou, Qun yong; Balboni, Gianfranco; Aboussaouira, Touria; Feige, Jean jacques; Benharouga, Mohamed; Alfaidy, Nadia | PLACENTA | - |
| Genetically Encodable Bacterial Flavin Transferase for Fluorogenic Protein Modification in Mammalian Cells | 1-Jan-2017 | Kang, Myeong Gyun; Park, Jumi; Balboni, Gianfranco; Lim, Mi Hee; Lee, Changwook; Rhee, Hyun Woo | ACS SYNTHETIC BIOLOGY | - |
| DESIGN, SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF NEW DNA METHYLTRANSFERASE INHIBITORS | 1-Jan-2016 | Balboni, Gianfranco; Deplano, Alessandro; Demurtas, Monica; Arimondo, Paola B.; Masson, Veronique; Onnis, Valentina | - | - |
| DIHYDROQUINAZOLINE BENZYLAMIDES AS ACETYLCHOLINESTERASE AND BUTYRYLCHOLINESTERASE INHIBITORS | 1-Jan-2016 | Onnis, Valentina; Balboni, Gianfranco; Deplano, Alessandro; Demurtas, Monica; Buyn, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Catto, Marco; Pisani, Leonardo; Carotti, Angelo | - | - |
| Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones | 1-Jan-2016 | Onnis, Valentina; Demurtas, Monica; Deplano, Alessandro; Balboni, Gianfranco; Baldisserotto, A; Manfredini, S; Pacifico, S; Liekens, S; Balzarini, J. | MOLECULES | - |
| Effect of the T-type channel blocker KYS-05090S in mouse models of acute and neuropathic pain | 1-Jan-2016 | M'Dahoma, Saïd; Gadotti, Vinicius M; Zhang, Fang Xiong; Park, Byeongyeon; Nam, Ji Hye; Onnis, Valentina; Balboni, Gianfranco; Lee, Jae Yeol; Zamponi, Gerald W. | PFLÜGERS ARCHIV | - |
| Attenuating Ischemic Disruption of K+ Homeostasis in the Cortex of Hypoxic-Ischemic Neonatal Rats: DOR Activation vs. Acupuncture Treatment | 1-Jan-2016 | Chao, Dongman; Wang, Qinyu; Balboni, Gianfranco; Ding, Guanghong; Xia, Ying | MOLECULAR NEUROBIOLOGY | - |
| Prokineticins are neuroprotective in models of cerebral ischemia and ischemic tolerance in vitro | 1-Jan-2016 | Landucci, E; Lattanzi, R; Gerace, E; Scartabelli, T; Balboni, Gianfranco; Negri, L; Pellegrini Giampietro, De | NEUROPHARMACOLOGY | - |
| Synthesis and SIRT1 modulation studies of amides and hydrazides of benzoic acid incorporating a (2-trifluoromethylpyridin-4-yl)amino moiety | 1-Jan-2015 | Congiu, Cenzo; Balboni, Gianfranco; Onnis, Valentina | - | - |
| TRPV1 modulators: synthesis and in vitro evaluation of 1-heteroarylpiperidinecarboxamide and piperazinylurea derivatives | 1-Jan-2015 | Congiu, Cenzo; Onnis, Valentina; Balboni, Gianfranco; Schiano Moriello, A; Di Marzo, V; De Petrocellis, L. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Dihydroquinazoline and Triazinedione Derivatives as Prok1 and Prok2 receptor antagonists in HEK-293 transfected cells | 1-Jan-2015 | Balboni, Gianfranco; Congiu, Cenzo; Deplano, Alessandro; Demurtas, Monica; Buyn, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Sbai, Oualid; Rondard, Philippe; Onnis, Valentina | - | - |
| Prokineticin 2 upregulation in the peripheral nervous system has a major role in triggering and maintaining neuropathic pain in the chronic constriction injury model | 1-Jan-2015 | Lattanzi, R; Maftei, D; Marconi, V; Florenzano, F; Franchi, S; Borsani, E; Rodella, Lf; Balboni, Gianfranco; Salvadori, S; Sacerdote, P; Negri, L. | BIOMED RESEARCH INTERNATIONAL | - |
| Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity | 1-Jan-2015 | Severini, C.; Lattanzi, R.; Maftei, D.; Marconi, V.; Ciotti, M. T.; Petrocchi Passeri, P.; Florenzano, F.; Del Duca, E.; Caioli, S.; Zona, C.; Balboni, Gianfranco; Salvadori, S.; Nistico, R.; Negri, L. | SCIENTIFIC REPORTS | - |
| Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives | 1-Jan-2015 | Sakakibara, Norikazu; Balboni, Gianfranco; Congiu, Cenzo; Onnis, Valentina; Demizu, Yosuke; Misawa, Takashi; Kurihara, Masaaki; Kato, Yoshihisa; Maruyama, Tokumi; Toyama, Masaaki; Okamoto, Mika; Baba, Masanori | ANTIVIRAL CHEMISTRY & CHEMOTHERAPY | - |
Icon legend
- files available
- files available on intranet
- files available for authorized users
- files available for administrators
- files under embargo
- no files available