Tandem Baeyer–Villiger/Wittig/oxa-Michael addition: One-step to 5-substituted γ-lactones
Barranco S.;Caboni P.;Frongia A.
2023-01-01
Abstract
The results reported in this study provide a practical protocol for the construction, in one single step of synthetically important γ-lactones in good yields starting from α-hydroxy cyclobutanone, H2O2 and several stabilized phosphonium ylides. Our synthetic strategy relies on a tandem Baeyer–Villiger oxidation/Wittig reaction/oxa-Michael addition.File | Size | Format | |
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1-s2.0-S0040403923002447-main.pdf Solo gestori archivio
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Tetrahedron_Letters 2023.pdf open access
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